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doi: 10.3389/fimmu.2017.00196 153 LuchettiSvan EdenCGSchuurmanKvan StrienMESwaabDFHuitingaI

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Particle & Particle Systems Characterization 0 , 1800414, (2018)

In vitro cellular senescence models (such as senescence models of human fibroblasts, hepatocytes, and nerve cells) are common tools for studying aging mechanisms and interventional drugs

38 Another 3-year study showed an improvement in lung function in a group of COPD patients consuming higher amounts of fruits and vegetables

However, the expression of this entire set of genes was down-regulated by miR-4488 at 24 h of starvation, whereas the proinflammatory genes were also down-regulated at 48 h, often even more strongly than at 24 h (Fig 6B)